St. John’s wort danger.

St. John’s wort -> CYP3A4 (+140%):  … biotransformation > 50% of all prescription medications. … should be strongly discouraged in the elderly.“ Clinical Assessment of Botanical Supplementation on Cytochrome P450 Phenotypes in the Elderly: St. John’s wort, Garlic oil, Panax ginseng, and Ginkgo biloba, Drugs Aging. 2005; 22(6): 525–539.

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